Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4311
Gene Symbol: MME
MME
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.300 Biomarker LHGDN However, these novel findings add to the weight of evidence supporting the involvement of neprilysin in the aetiology of Alzheimer's disease. 17928142

2007
Entrez Id: 4311
Gene Symbol: MME
MME
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.300 AlteredExpression LHGDN We found a significant decrease in neprilysin mRNA levels in both AD and NA compared to control cases. 16226260

2005
Entrez Id: 4311
Gene Symbol: MME
MME
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.300 GeneticVariation LHGDN We used denaturing high-performance liquid chromatography to screen the neprilysin gene (NEP) for single nucleotide polymorphisms (SNPs) in 257 Chinese sporadic Alzheimer's disease patients and 242 cognitive normal controls. 15860464

2005
Entrez Id: 4311
Gene Symbol: MME
MME
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.300 GeneticVariation LHGDN Our findings suggest that the GT-repeat polymorphism in the promoter region of the NEP gene or some other unknown polymorphisms, which are in a linkage disequilibrium, confer a susceptibility to late-onset AD. 14739539

2004
Entrez Id: 4311
Gene Symbol: MME
MME
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.300 AlteredExpression LHGDN In sections from AD patients we observed a clear inverse relationship between neprilysin and A beta peptide levels in the vasculature, implicating neprilysin in cerebral amyloid angiopathy. 12387451

2002