DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Squamous cell carcinoma ×

Gene: MDM2 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	4193
Gene Symbol:	MDM2

MDM2

CUI:	C0007137
Disease:	Squamous cell carcinoma

Squamous cell carcinoma

0.100

AlteredExpression

LHGDN

The role of NPM, p14arf and MDM2 in precursors of bronchial squamous cell carcinoma.

18480108

2008

Entrez Id:	4193
Gene Symbol:	MDM2

MDM2

CUI:	C0007137
Disease:	Squamous cell carcinoma

Squamous cell carcinoma

0.100

AlteredExpression

LHGDN

SUMO-1 may be useful as a novel target for therapy in oral SCC as well as a clinical indicator for tumor recurrence together with Mdm2.

17671677

2007

Entrez Id:	4193
Gene Symbol:	MDM2

MDM2

CUI:	C0007137
Disease:	Squamous cell carcinoma

Squamous cell carcinoma

0.100

Biomarker

LHGDN

Alterations of the p14ARF-p53-MDM2 pathway in oral squamous cell carcinoma: MDM2 overexpression is a common event.

16142358

2005

Entrez Id:	4193
Gene Symbol:	MDM2

MDM2

CUI:	C0007137
Disease:	Squamous cell carcinoma

Squamous cell carcinoma

0.100

AlteredExpression

LHGDN

The expression of murine double minute 2 is a favorable prognostic marker in esophageal squamous cell carcinoma without p53 protein accumulation.

12052755

2002