Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN A haplotype variation affecting the mitochondrial transportation of hMYH protein could be a risk factor for colorectal cancer in Chinese. 18811933

2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN The role of MYH gene in genetic predisposition to colorectal cancer: another piece of the puzzle. 18495334

2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN Contribution of common monoallelic MUTYH gene variants in German patients with familial colorectal cancer. 18503156

2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 Biomarker LHGDN Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population. 18271935

2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 Biomarker LHGDN Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population. 18823566

2008
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN Somatic mutation of MutYH in Tunisian patients with sporadic colorectal cancer. 18022921

2007
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN Biallelic germline mutations in MYH are associated with colorectal neoplasms, which develop through a pathway involving somatic inactivation of APC. 17031395

2006
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 Biomarker LHGDN [MYH and colorectal cancer. A significant advance?]. 16938257

2006
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN Association of MUTYH and colorectal cancer. 16804517

2006
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN Germline susceptibility to colorectal cancer due to base-excision repair gene defects. 15931596

2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN The potential for increased clinical sensitivity in genetic testing for polyposis colorectal cancer through the analysis of MYH mutations in North American patients. 15635083

2005
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN Loss of heterozygosity in at least one of four loci in MYH was detected in eight (47%) of 17 colorectal tumors from monoallelic MYH gene mutation carriers but in only two (20%) of 10 colorectal tumors from biallelic MYH gene mutation carriers. 15523092

2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN Role of inherited defects of MYH in the development of sporadic colorectal cancer. 15034862

2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation LHGDN Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer. 14991577

2004
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 PosttranslationalModification LHGDN Defective human MutY phosphorylation exists in colorectal cancer cell lines with wild-type MutY alleles. 12966098

2003