Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4548
Gene Symbol: MTR
MTR
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.100 GeneticVariation LHGDN In conclusion, the presence of three or more polymorphic alleles for MTHFR C677T, MTHFR A1298C, MTR A2756G, and RFC1 A80G, and plasma Hcy concentrations higher than 4.99 micromol/L are maternal risk factors for DS. 18273817

2008
Entrez Id: 4548
Gene Symbol: MTR
MTR
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.100 GeneticVariation LHGDN In conclusion, our results provide evidences that homocysteine and MTR genetic polymorphism are two potent risk factors for mothers to have a DS child in Sicily. 12923861

2003