Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6285
Gene Symbol: S100B
S100B
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.400 AlteredExpression LHGDN We further demonstrate in DS NPCs that S100B is constitutively overexpressed, that overexpression leads to increased reactive oxygen species (ROS) formation and activation of stress response kinases, and that activation of this pathway results in compensatory AQP4 expression. 17984171

2008
Entrez Id: 6285
Gene Symbol: S100B
S100B
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.400 AlteredExpression LHGDN The higher levels of S100B in DS patients may reflect a general and persistent increase in the extracellular space and may be associated with neurodegenerative lesions observed in DS patients. 15820773

2005