Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 875
Gene Symbol: CBS
CBS
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.100 AlteredExpression LHGDN To analyze the possible role of CBS in Down syndrome, we have produced several lines of transgenic mice expressing the human CBS gene. 16541333

2006
Entrez Id: 875
Gene Symbol: CBS
CBS
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.100 AlteredExpression LHGDN The over-expression of CBS may cause the developmental abnormality in cognition in DS children and that may lead to AD in DS adults. 16274669

2005
Entrez Id: 875
Gene Symbol: CBS
CBS
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.100 AlteredExpression LHGDN Subsequent quantitative analysis of CBS and PDXK revealed levels comparable between DS and controls. 15082224

2004
Entrez Id: 875
Gene Symbol: CBS
CBS
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.100 AlteredExpression LHGDN The results of this study with clinically relevant cell line models suggest potential mechanisms for disparate patterns of CBS gene expression in DS and non-DS myeloblasts and may, in part, explain the greater sensitivity to chemotherapy shown by patients with DS AML. 12393509

2003