Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
CUI: C0021368
Disease: Inflammation
Inflammation 		0.040 AlteredExpression LHGDN The activation of neutrophil elastase-mediated fibrinolysis is not sufficient to overcome the fibrinolytic shutdown of disseminated intravascular coagulation associated with systemic inflammation. 17397908

2007
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
CUI: C0021368
Disease: Inflammation
Inflammation 		0.040 AlteredExpression LHGDN Human leukocyte elastase and cathepsin G are specific inhibitors of C5a-dependent neutrophil enzyme release and chemotaxis. 15140022

2004
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
CUI: C0021368
Disease: Inflammation
Inflammation 		0.040 Biomarker LHGDN Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates. 12114510

2002
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
CUI: C0021368
Disease: Inflammation
Inflammation 		0.040 Biomarker LHGDN Novel effects of neutrophil-derived proteinase 3 and elastase on the vascular endothelium involve in vivo cleavage of NF-kappaB and proapoptotic changes in JNK, ERK, and p38 MAPK signaling pathways. 12444202

2002