Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
CUI: C0021368
Disease: Inflammation
Inflammation 		0.040 Biomarker LHGDN A theme is developing that the granulocyte protease, PR3, is an exogenous caspase-like molecule that can sidestep intracellular caspase functions at sites of inflammation. 14675038

2004
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
CUI: C0021368
Disease: Inflammation
Inflammation 		0.040 Biomarker LHGDN The data demonstrate that PR3 and HNE have specific, fundamental roles in endothelial responses during inflammation. 12444202

2002
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
CUI: C0021368
Disease: Inflammation
Inflammation 		0.040 Biomarker LHGDN These findings suggest that neutrophil PR3 activates oral epithelial cells through G protein-coupled PAR-2 and actively participates in the process of inflammation such as periodontitis. 12370398

2002
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
CUI: C0021368
Disease: Inflammation
Inflammation 		0.040 Biomarker LHGDN Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates. 12114510

2002