Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 604
Gene Symbol: BCL6
BCL6
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.200 AlteredExpression LHGDN We found that activation of STAT5 downregulates BCL6 expression in B-lymphoma cells and other hematopoietic cell lines. 16819511

2007

Entrez Id: 604
Gene Symbol: BCL6
BCL6
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.200 Biomarker LHGDN Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas. 17360630

2007

Entrez Id: 604
Gene Symbol: BCL6
BCL6
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.200 Biomarker LHGDN Here we demonstrate that the transcriptional repressor Bcl-6 mediates this phenotype by directly repressing ATR in centroblasts and lymphoma cells. 17558410

2007

Entrez Id: 604
Gene Symbol: BCL6
BCL6
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.200 AlteredExpression LHGDN These data confirm PDCD2 as a target of BCL6 and support the concept that repression of PDCD2 by BCL6 is likely important in the pathogenesis of certain human lymphomas. 17468402

2007

Entrez Id: 604
Gene Symbol: BCL6
BCL6
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.200 Biomarker LHGDN High BCL6 expression predicts better prognosis, independent of BCL6 translocation status, translocation partner, or BCL6-deregulating mutations, in gastric lymphoma. 16772602

2006

Entrez Id: 604
Gene Symbol: BCL6
BCL6
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.200 GeneticVariation LHGDN We analyzed the distribution and association of bcl-6 and p53 mutations in 55 consecutive bcl-2/Jh+ lymphoma samples derived from 43 patients obtained at the time of diagnosis and, in 5 of these patients, during follow-up. 12217802

2002

Entrez Id: 604
Gene Symbol: BCL6
BCL6
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.200 Biomarker LHGDN The proto-oncogene BCL-6 in normal and malignant B cell development. 12469325

2002

Entrez Id: 604
Gene Symbol: BCL6
BCL6
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.200 Biomarker LHGDN FISH analysis with a YAC probe improves detection of LAZ3/BCL6 rearrangement in non-Hodgkin's lymphoma. 11920179

2000