Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Depletion of intracellular zinc increases expression of tumorigenic cytokines VEGF, IL-6 and IL-8 in prostate cancer cells via NF-kappaB-dependent pathway. 18615482

2008

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis. 18780829

2008

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Translationally regulated C/EBP beta isoform expression upregulates metastatic genes in hormone-independent prostate cancer cells. 18512730

2008

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker LHGDN Osteopontin and interleukin-8 expression is independently associated with prostate cancer recurrence. 18593988

2008

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Regulation of interleukin-8 expression in human prostate cancer cells by insulin-like growth factor-I and inflammatory cytokines. 17513150

2007

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells. 16541418

2006

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Serum interleukin-8 is elevated in men with prostate cancer and bone metastases. 15453805

2004

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 AlteredExpression LHGDN Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells. 12839933

2003