DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Thyroid Neoplasm ×

Gene: TP73 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	7161
Gene Symbol:	TP73

TP73

CUI:	C0040136
Disease:	Thyroid Neoplasm

Thyroid Neoplasm

0.060

AlteredExpression

LHGDN

Indeed, depletion of p73 by small interfering RNA in thyroid cancer cells resulted in a reduced transcriptional activity of p53.

2008