Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer. 17805961

2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN The C1772T genetic polymorphism in human HIF-1alpha gene associates with expression of HIF-1alpha protein in breast cancer. 18949419

2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Extracellular matrix and HIF-1 signaling: the role of prolidase. 17999410

2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Mechanism of leptin expression in breast cancer cells: role of hypoxia-inducible factor-1alpha. 17653093

2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Correlation between the expression of aquaporin 1 and hypoxia-inducible factor 1 in breast cancer tissues. 18563339

2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Rare variant of hypoxia-inducible factor-1alpha (HIF-1A) and breast cancer risk in Korean women. 18160046

2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Single nucleotide polymorphisms in the hypoxia-inducible factor-1alpha (HIF-1alpha) gene in human sporadic breast cancer. 18279708

2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN High frequency of HIF-1alpha overexpression in BRCA1 related breast cancer. 18030615

2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Basic FGF augments hypoxia induced HIF-1-alpha expression and VEGF release in T47D breast cancer cells. 17676480

2007
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Hypoxia inducible factor-1alpha correlates with VEGF-C expression and lymphangiogenesis in breast cancer. 16555123

2006
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Hypoxia-inducible factor-1alpha expression predicts a poor response to primary chemoendocrine therapy and disease-free survival in primary human breast cancer. 16899602

2006
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Hypoxia-inducible factor-1alpha is associated with angiogenesis, and expression of bFGF, PDGF-BB, and EGFR in invasive breast cancer. 15656883

2005
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Mutation analysis of the HIF-1alpha oxygen-dependent degradation domain in invasive breast cancer. 16337862

2005
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha. 15342390

2004
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Hypoxia-inducible factor 1 alpha in high-risk breast cancer: an independent prognostic parameter? 15084243

2004
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. 14559790

2003