Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 GeneticVariation LHGDN The MTHFR 1298A>C and the MTRR 66A>G genotypes were associated with an increased risk of HCC in this Korean population. 19035314

2008

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 GeneticVariation LHGDN To date, no study has been conducted on MTHFR and hepatocellular carcinoma (HCC) using a population-based design. 17503006

2007

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 AlteredExpression LHGDN This study supports the hypothesis that reduced MTHFR activity and enhanced TYMS activity, both of which are essential elements in minimizing uracil misincorporation into DNA, may protect against the development of HCC. 17659576

2007