Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.400 AlteredExpression LHGDN These results reveal a new AP-1 site within the TRAIL promoter functionally involved in TGF-beta-induced TRAIL expression and apoptosis in hepatomas. 18644981

2008

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.400 AlteredExpression LHGDN The combined delivery of CYLD and TRAIL may be a new useful strategy for hepatocellular carcinoma or other tumor cells with enhanced NF-kappaB activity. 16627981

2007

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.400 AlteredExpression LHGDN TRAIL expression from a viral vector activated the Caspase-3 enzymatic capacity, and hepatocellular carcinoma cells were sensitive to TRAIL. 16082383

2006

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.400 AlteredExpression LHGDN TRAIL expressed on the surface of hepatocellular carcinoma cells by cytokines or cytostatic drugs might contribute to an alternative mechanism that enables tumors to evade immune surveillance by inducing apoptosis of activated human lymphocytes 15809718

2005

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.400 Biomarker LHGDN We identified the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as a mediator of TGF-beta-induced apoptosis in hepatoma cells. 15962328

2005

Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.400 AlteredExpression LHGDN sensitization hepatoma cells to TRAIL induced apoptosis through DR5 upregulation and NF-kappa B inactivation is sensitized by interferon-alpha 12642868

2003