DisGeNET - a database of gene-disease associations

Source: MGD

Disease: Multi-core congenital myopathy ×

Gene: ITGA7 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3679
Gene Symbol:	ITGA7

ITGA7

CUI:	C0270962
Disease:	Multi-core congenital myopathy

Multi-core congenital myopathy

0.200

Biomarker

MGD

α6β1 and α7β1 integrins are required in Schwann cells to sort axons.

24227711

2013

Entrez Id:	3679
Gene Symbol:	ITGA7

ITGA7

CUI:	C0270962
Disease:	Multi-core congenital myopathy

Multi-core congenital myopathy

0.200

Biomarker

MGD

Defective integrin switch and matrix composition at alpha 7-deficient myotendinous junctions precede the onset of muscular dystrophy in mice.

12588796

2003

Entrez Id:	3679
Gene Symbol:	ITGA7

ITGA7

CUI:	C0270962
Disease:	Multi-core congenital myopathy

Multi-core congenital myopathy

0.200

Biomarker

MGD

Absence of integrin alpha 7 causes a novel form of muscular dystrophy.

9354797

1997