DisGeNET - a database of gene-disease associations

Source: MGD

Disease: Aicardi-Goutieres Syndrome 2 ×

Gene: TREX1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	11277
Gene Symbol:	TREX1

TREX1

CUI:	C3489724
Disease:	Aicardi-Goutieres Syndrome 2

Aicardi-Goutieres Syndrome 2

0.500

Biomarker

MGD

The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.

27496731

2016

Entrez Id:	11277
Gene Symbol:	TREX1

TREX1

CUI:	C3489724
Disease:	Aicardi-Goutieres Syndrome 2

Aicardi-Goutieres Syndrome 2

0.500

Biomarker

MGD

Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.

23972988

2013

Entrez Id:	11277
Gene Symbol:	TREX1

TREX1

CUI:	C3489724
Disease:	Aicardi-Goutieres Syndrome 2

Aicardi-Goutieres Syndrome 2

0.500

Biomarker

MGD

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis.

15254239

2004