DisGeNET - a database of gene-disease associations

Gene: MAP2K1 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	5604
Gene Symbol:	MAP2K1

MAP2K1

CUI:	C2063866
Disease:	Depressive Disorder, Treatment-Resistant

Depressive Disorder, Treatment-Resistant

0.310

Biomarker

PSYGENET

Our findings support the hypothesis that BDNF and MEK1 mRNA expression levels are more obviously decreased in patients with TRD.

2014