Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5551
Gene Symbol: PRF1
PRF1
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD To study the expression of perforin and granzyme B (GzmB) in the lungs of asthmatic rats and the effect of recombinant human growth hormone (rhGH) on the expression. 21426642

2011

Entrez Id: 5551
Gene Symbol: PRF1
PRF1
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD Perforin and GzmB may play important roles in the pathogenesis of asthma. rhGH treatment can inhibit apoptosis of airway epithelial cells and airway remodeling, possibly through a reduction in perforin and GzmB expression. 21426642

2011

Entrez Id: 5551
Gene Symbol: PRF1
PRF1
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD [Expression of perforin and granzyme B in asthmatic rats and intervention of recombinant human growth hormone]. 21426642

2011

Entrez Id: 5551
Gene Symbol: PRF1
PRF1
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD Compared with the control group, perforin and GzmB expression in the lungs in the untreated asthma group increased significantly. 21426642

2011

Entrez Id: 5551
Gene Symbol: PRF1
PRF1
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD The rhGH-treated asthma group demonstrated significantly decreased perforin (0.48 ± 0.08 vs 0.63 ± 0.08; P<0.05) and GzmB (0.44 ± 0.13 vs 0.71 ± 0.15; P<0.05) expression in the lungs compared with the untreated asthma group. 21426642

2011