Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE <b>Abbreviations:</b> AAP: American Academy of Pediatrics; BMI: body mass index; BP: blood pressure; cm: centimeter; DBP: diastolic blood pressure; HT: hypertension; kg: kilograms; m: meter; NHANES: National Health and Nutrition Examination Survey; ROC: receiver operating characteristic curve; SBP: systolic blood pressure; SBPHR: systolic blood pressure-to-height ratio; SD: standard deviation; WC: waist circumference; WHR: waist-to-height ratio. 31038015

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Hypertension was defined as SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg or currently taking antihypertensive medicines. 29553846

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Hypertension was defined as SBP at least 140 mmHg and/or DBP at least 90 mmHg, or current hypertension treatment, and was age-standardized to WHO world population. 30308598

2018

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 AlteredExpression BEFREE High blood pressure levels at 10 gestational weeks significantly increased the risk of SGA birth (SBP: RR = 1.32, 95% CI: 1.11-1.56; DBP: RR = 1.10, 95% CI: 1.05-1.14). 30631132

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Hypertension was defined as SBP at least 140 mmHg and/or DBP at least 90 mmHg, or current hypertension treatment, and was age-standardized to WHO world population. 30817448

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Hypertension was measured as SBP at least 140 mmHg or DBP at least 90 mmHg.Random-effects meta-analysis was used. 31166251

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Hypertension was defined as SBP at least 130 mmHg or DBP at least 80 mmHg, taking antihypertensive medicine or self-report. 31356404

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE SBP control rate among women with hypertension was the highest in 40-49 years (67.0%) but without linear trend by age group. 31190479

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE A linear relationship was revealed between intradialytic SBP in IDH patients, indicating that the pre-HD and intra-HD SBP were correlated with post-HD SBP. 30325241

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE According to three independent measurements of SBP in 1987, 1989, and 1992, cases of the same age and sex with continuous SBP at least 75 percentile were classified as the high-blood pressure (BP) group, whereas those with SBP less than 50 percentile were classified as the normal-BP group. 28060189

2017

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Achievement of target SBP without attention to decrease in DBP can increase cardiovascular morbidity in treated arterial hypertension: the Campania Salute Network. 31205199

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 AlteredExpression BEFREE Adjusted multiple linear regression models elicited positive associations of age (βa = 0.152, p = 0.001) and duration of hypertension (βa = 0.132, p = 0.003) with achieved level of SBP as well as BMI (βa = 0.135, p = 0.002) with DBP. 28129402

2017

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE After 1 month, superior SBP (-3.1 mmHg, P = 0.02) and DBP (-2.8 mmHg, P < 0.001) reductions were observed with perindopril/indapamide/amlodipine, which were even more pronounced after excluding white-coat effect in the sustained hypertension population (-5.3/-3.7 mmHg). 28306636

2017

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE After adjusted for traditional risk factors including brachial SBP, both central SBP, and AIx@75 remained significantly associated with CVD, with odds ratio and 95% confidence interval of 1.09 (1.08-1.31) and 1.20 (1.15-1.42), respectively.Diabetic patients with hypertension, ageing, male gender, and presence of CVD are independent risk factors of central BP increase; and increased central SBP and AIx@75 are significantly associated with CVD. 29049227

2017

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE After Bonferroni correction the polymorphism rs4680 (ValMet) in COMT was significantly associated with lower SBP in participants treated with CCBs (P = .009) with an especially strong impact in elderly individuals (age ≥ 70) alone (Δ = -14.08 mm Hg, P = .0005).These results underline the important role of estrogens and catecholamines in hypertension and the importance of genotype dependent, age-related adjustments of calcium-channel blocker treatment. 28746172

2017

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE After stratifying the subjects according to blood pressure and blood glucose, the positive relationship between RHR and UACR remained in the subjects with normal blood pressure and normal glucose tolerance, while in the hypertension (SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg) group and the diabetic mellitus (FPG ≥ 7.0 mmol/L and/or PPG ≥ 11.1 mmol/L) group, the relationship disappeared. 31534974

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE An increase of 0.1 in NDVI corresponded to a reduction in SBP of 1.39 mmHg (95% CI: 1.86, -0.93) and lower odds of hypertension (OR = 0.76, 95% CI: 0.69, 0.82). 31672364

2020

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Asian people with hypertension: SBP: MD -7.75 mmHg (95% CI:-11,44 to -4.07; P < 0.0001) nine studies, 501 participants; DBP: MD -2.68 mmHg (95% CI: -4.21 to -1.15; P = 0.0006). 28391629

2017

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Childhood hypertension and elevated blood pressure were defined as SBP and/or DBP ≥95th and ≥90th age- and gender-specific percentile, respectively. 31826379

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Chronic VNS therapy slowed the progression of HTN through an attenuation of SBP and by preserving HRV. 30766489

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Cox proportional hazards regression revealed that SBP (1.02[1.01, 1.02]) and more insomnia symptoms (1.11[1.01, 1.21]) were significant predictors of hypertension for all age groups. 30742871

2019

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE Despite having higher renal expression of <i>Nlrp3, Casp-1</i> and <i>Il-1β</i>, Ang II-induced hypertension (SBP: 139±7 mmHg) was unaffected by co-infusion of the NLRP3 inflammasome inhibitor, MCC950 (10 mg/kg/d; SBP: 145±10 mmHg). 28659507

2017

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE Distinguishing trajectories allows identification of subgroups at risk of hypertension and cardiovascular disease later in life and in addition can inform the design of targeted interventions to attenuate high SBP and DBP trajectories over time and maintain normal trajectories. 28234673

2017

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 GeneticVariation BEFREE Each interquartile increment in walkability was associated with the lower blood pressure outcomes of DBP (β = -0.358, 95% CI: -0.42, -0.29 mmHg), SBP (β = -0.833, 95% CI: -0.95, -0.72 mmHg) as well as reduced hypertension risk (RR = 0.970, 95% CI: 0.96, 0.98). 29398408

2018

Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.100 Biomarker BEFREE EMPOWER-H also significantly reduced both office and home SBP and DBP, decreased office-measured weight and consumption of high-salt and high-fat foods (all P<.005), and increased intake of fruit and vegetables, minutes of aerobic exercise, and hypertension knowledge (all P<.05). 28928111

2017