×
Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
Similarly, SOR also enhanced the expression of LC3-II and Caspase-3 in PCOS while substantially reducing the level of mTORC2 and P62 .
31256441 2020
×
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
In conclusion, MALAT1 reduction was identified in GCs, which may contribute to the pathophysiological processes of PCOS by regulating TGFβ signaling through sponging miR-125b and miR-203a .
31557499 2020
×
Entrez Id: 5618
Gene Symbol: PRLR
PRLR
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
Association between prolactin receptor expression and proliferation in the endometrium of obese women with polycystic ovary syndrome .
31389293 2020
×
Entrez Id: 3304
Gene Symbol: HSPA1B
HSPA1B
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
In conclusion, increased HSP72 expression to exercise over an 8-week period was seen in control but not in PCOS women, suggesting that there is an impairment of HSP72 expression in response to exercise in these women.
31734892 2020
×
Entrez Id: 6781
Gene Symbol: STC1
STC1
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
The findings indicate that STC-1 expression is not steroid hormone mediated , although secretory-phase STC-1 expression was blunted in PCOS .
31494675 2020
×
Entrez Id: 6285
Gene Symbol: S100B
S100B
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
S100 -A9 protein in exosomes derived from follicular fluid promotes inflammation via activation of NF-κB pathway in polycystic ovary syndrome .31568644 2020
×
Entrez Id: 10657
Gene Symbol: KHDRBS1
KHDRBS1
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
Similarly, SOR also enhanced the expression of LC3-II and Caspase-3 in PCOS while substantially reducing the level of mTORC2 and P62 .
31256441 2020
×
Entrez Id: 57587
Gene Symbol: CFAP97
CFAP97
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
Treatment with SPIOMET, a low-dose combination of spironolactone (to antagonize androgen and mineralocorticoid effects, and to activate BAT thereby raising energy expenditure), pioglitazone (to raise circulating HMW adiponectin concentrations) and metformin, is an alternative approach that holds the potential to revert the PCOS phenotype.
31663293 2020
×
Entrez Id: 2965
Gene Symbol: GTF2H1
GTF2H1
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
Similarly, SOR also enhanced the expression of LC3-II and Caspase-3 in PCOS while substantially reducing the level of mTORC2 and P62 .
31256441 2020
×
Entrez Id: 116842
Gene Symbol: LEAP2
LEAP2
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
We found that circulating LEAP-2 and ghrelin levels were decreased in women with PCOS as compared with controls.
31526069 2020
×
Entrez Id: 6271
Gene Symbol: S100A1
S100A1
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
S100 -A9 protein in exosomes derived from follicular fluid promotes inflammation via activation of NF-κB pathway in polycystic ovary syndrome .31568644 2020
×
Entrez Id: 406919
Gene Symbol: MIR130A
MIR130A
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
Based on our finding, we predict that competitive binding of HOTAIR to miR-130a may act as a novel target for the molecular treatment of PCOS .
31733099 2020
×
Entrez Id: 574411
Gene Symbol: MIR451A
MIR451A
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
In the present study, miR-451a could diagnose PCOS with 100% sensitivity and 100% specificity.
31730174 2020
×
Entrez Id: 23636
Gene Symbol: NUP62
NUP62
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
Similarly, SOR also enhanced the expression of LC3-II and Caspase-3 in PCOS while substantially reducing the level of mTORC2 and P62 .
31256441 2020
×
Entrez Id: 574413
Gene Symbol: MIR409
MIR409
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
Effect of microRNA-409 on the pathogenesis of polycystic ovary syndrome .
30915729 2019
×
Entrez Id: 969
Gene Symbol: CD69
CD69
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
Furthermore, the levels of CD69 and IFN-γ were significantly decreased and the level of PD-1 was increased in both CD4<sup>+</sup> and CD8<sup>+</sup> T cells from infertile patients with PCOS (P < 0.05).
30988342 2019
×
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
<b>Abbreviations</b>: AUC: area under curve; BMI: body mass index; C: cholesterol; CI: confidence interval; DBP: diastolic blood pressure; DHEAS: dehydroepiandrosterone sulfate; FG: Ferriman-Gallway; FSH: follicle stimulating hormone; GHQ: general health questionnaire; HA: hyperandrogenism; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; HWR: hip waist ratio; LDL-C: low-density lipoprotein cholesterol; LH: luteinizing hormone; LH: luteinizing hormone; LHR: lutropin receptor; O: oligomenorrhea; OR: odds ratio; PCO: polycystic ovaries; PCO: polycystic ovary ; PCOS: polycystic ovary syndrome ; PCR: polymerase chain reaction; ROC: receiver operating curve; SBP : systolic blood pressure; SE: standard error of coefficient; SNP: single nucleotide polymorphism; TG: triglycerides; TSH: thyroid stimulating hormone; VD: vitamin D.
30958034 2019
×
Entrez Id: 653361
Gene Symbol: NCF1
NCF1
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
Regardless of weight class, women with PCOS exhibited lipid-induced increases in leukocytic ROS generation and p47phox mRNA and protein content as well as plasma TBARS compared with lean control subjects.
31298704 2019
×
Entrez Id: 9235
Gene Symbol: IL32
IL32
Polycystic Ovary Syndrome
0.010
GeneticVariation
BEFREE
There were significant differences between PCOS and healthy women regarding IL-17A rs2275913 alleles, genotypes frequencies (p=0.005, and 0.01, respectively) and the allelic distribution of IL-32 rs9927163 SNP (p=0.03).
30848577 2019
×
Entrez Id: 574444
Gene Symbol: MIR491
MIR491
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
Metformin likely improves endometrial receptivity through downregulating the expression of miR-491 -3p and miR-1910-3p, thereby increasing the expression of HOXA10 and ITGB3 in the endometrium of PCOS women.
30599813 2019
×
Entrez Id: 100133941
Gene Symbol: CD24
CD24
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
In addition, it was observed that the fraction of CD24 (+) cumulus GCs decreases in PCOS patients compared to that of controls.
31624236 2019
×
Entrez Id: 7681
Gene Symbol: MKRN3
MKRN3
Polycystic Ovary Syndrome
0.010
GeneticVariation
BEFREE
The prevalence of polycystic ovarian syndrome was 9.1% in patients with CPP due to MKRN3 mutations and 5.9% in those with idiopathic CPP.
31671431 2019
×
Entrez Id: 2645
Gene Symbol: GCK
GCK
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
PCOS resulted in a decrease in liver GK and an increase in liver HK specific activity, whereas quercetin increased both liver HK and GK activity.30103849 2019
×
Entrez Id: 6870
Gene Symbol: TACR3
TACR3
Polycystic Ovary Syndrome
0.010
AlteredExpression
BEFREE
The aim of this study was to analyze the expression of NKB/NK3R and KISS1/KISS1R in mural granulosa (MGCs) and cumulus cells (CCs) of PCOS women.
30382469 2019
×
Entrez Id: 3702
Gene Symbol: ITK
ITK
Polycystic Ovary Syndrome
0.010
Biomarker
BEFREE
Wound-healing, transwell, capsular bag models and rat PCO models assays were used to test the effects of gremlin on HLECs' migration, proliferation, EMT -specific protein α-smooth muscle actin（α-SMA）and development of PCO in rats.
31234714 2019