×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
GENOMICS_ENGLAND
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
CausalMutation
CLINVAR
Localization of specificity determining sites in cadherin cell adhesion molecules.
2317870 1990
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
Expression of E- and P-cadherin in gastric carcinomas.
2009537 1991
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role.
2070412 1991
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion.
8236461 1993
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
CLINVAR
E-cadherin gene mutations in human gastric carcinoma cell lines.
8127895 1994
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
A causal role for E-cadherin in the transition from adenoma to carcinoma.
9515965 1998
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
CausalMutation
CLINVAR
Identification of germ-line E-cadherin mutations in gastric cancer families of European origin.
9751616 1998
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CTD_human
E-cadherin germline mutations in familial gastric cancer.
9537325 1998
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
E-cadherin germline mutations in familial gastric cancer.
9537325 1998
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
CLINVAR
E-cadherin germline mutations in familial gastric cancer.
9537325 1998
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
UNIPROT
We screened five Korean familial gastric cancer patients to investigate germline mutations of the E-cadherin gene.
10319582 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
CausalMutation
CLINVAR
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
10072428 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
CausalMutation
CLINVAR
E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer.
10477433 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
CLINVAR
E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer.
10477433 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
BEFREE
More recently, germline E-cadherin/CDH1 mutations have been identified in hereditary diffuse gastric cancer kindred.
10593993 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
CLINVAR
Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells.
10037790 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CTD_human
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
10072428 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
CausalMutation
CLINVAR
Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation.
10433926 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
10072428 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
BEFREE
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
10072428 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
CausalMutation
CLINVAR
Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online.
10094558 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
BEFREE
These results demonstrate that germline mutation of the E-cadherin gene is a common cause of hereditary diffuse gastric cancer and suggest a role for these mutations in the incidence of breast cancer.
10477433 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
BEFREE
However, no germ-line mutation was detected, suggesting that a predisposition to FGC s by E-cadherin gene mutation is infrequent in Japanese cases.
10389930 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
PosttranslationalModification
BEFREE
Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer .
10973239 2000