Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression LHGDN Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK. 15908432

2005

Entrez Id: 8086
Gene Symbol: AAAS
AAAS
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. 24763052

2014

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.070 AlteredExpression BEFREE Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors. 11909640

2002

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.070 Biomarker BEFREE Reactive oxygen species-linked regulation of the multidrug resistance transporter P-glycoprotein in Nox-1 overexpressing prostate tumor spheroids. 16083877

2005

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.070 Biomarker BEFREE Redox regulation of P-glycoprotein-mediated multidrug resistance in multicellular prostate tumor spheroids. 10629088

2000

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.070 GeneticVariation LHGDN ABCB1 genetic variation influences the toxicity and clinical outcome of patients with androgen-independent prostate cancer treated with docetaxel. 18628469

2008

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.070 AlteredExpression BEFREE We hypothesize that early in prostate cancer progression, increased expression of YB-1 may increase P-gp activity which may in turn lower androgen levels in the prostate tumor cells. 15042610

2004

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.070 AlteredExpression BEFREE Down-regulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by reactive oxygen species. 11279018

2001

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.070 GeneticVariation BEFREE The MDR1 gene messenger ribonucleic acid (mRNA) was detected in two tumors using the Chinese hamster probe (one sphenoid wing meningioma and one metastatic prostate tumor) and in one CNS lymphoma using the human probe. 1682428

1991

Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 Biomarker LHGDN [Role of PTEN protein in multidrug resistance of prostate cancer cells]. 18702307

2008

Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.320 Biomarker CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.320 Biomarker LHGDN Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.320 Biomarker LHGDN Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer. 18615486

2008

Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 GeneticVariation LHGDN RNASEL and RNASEL-inhibitor variation and prostate cancer risk in Afro-Caribbeans. 18189233

2008

Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.020 PosttranslationalModification LHGDN The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells. 18056989

2008

Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.020 Biomarker LHGDN [Role of PTEN protein in multidrug resistance of prostate cancer cells]. 18702307

2008

Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human The Interaction between Pesticide Use and Genetic Variants Involved in Lipid Metabolism on Prostate Cancer Risk. 22919386

2012

Entrez Id: 10006
Gene Symbol: ABI1
ABI1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression BEFREE Moreover, ABI1 expression was significantly decreased in Gleason pattern 5 vs. pattern 4 (p = 0.0025) and 3 (p = 0.0012), indicating an association between low ABI1 expression and highly invasive prostate tumors. 31530281

2019

Entrez Id: 28
Gene Symbol: ABO
ABO
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model. 17013881

2007

Entrez Id: 29
Gene Symbol: ABR
ABR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 Biomarker CTD_human The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. 24763052

2014

Entrez Id: 29
Gene Symbol: ABR
ABR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 Biomarker BEFREE Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. 20470445

2010

Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression LHGDN Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT). 18000807

2008

Entrez Id: 39
Gene Symbol: ACAT2
ACAT2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression LHGDN Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT). 18000807

2008

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 GeneticVariation LHGDN Effects of ACE I/D polymorphism on prostate cancer risk, tumor grade and metastatis. 17465223

2007

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 Biomarker CTD_human Effects of ACE I/D polymorphism on prostate cancer risk, tumor grade and metastatis. 17465223

2007