Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human Analysis of cholinesterases in human prostate and sperm: implications in cancer and fertility. 20356562

2010

Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 Biomarker BEFREE Furthermore, the expression of prostate-specific receptor is increased significantly in prostate tumors in comparison with the matched normal prostate tissues using PCR and Southern blot analysis, suggesting a potential role of this tissue-specific G-protein coupled receptor in prostate cancer development. 11593396

2001

Entrez Id: 8310
Gene Symbol: ACOX3
ACOX3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression LHGDN Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer. 15599942

2005

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.240 Biomarker MGD Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine. 18940592

2008

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.240 Biomarker BEFREE With respect to prostate cancer, prostatic acid phosphatase, prostate‑specific antigen, prostate‑specific membrane antigen (PSMA), prostate stem cell antigen, T‑cell receptor γ alternate reading frame protein, transient receptor potential‑p8 and six‑transmembrane epithelial antigen of the prostate 1 are among the identified target antigens for prostate tumors. 30542701

2018

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.240 Biomarker MGD Transmembrane prostatic acid phosphatase (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma. 24039861

2013

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.240 AlteredExpression LHGDN Transcriptional activation of the human prostatic acid phosphatase gene by NF-kappaB via a novel hexanucleotide-binding site. 15240830

2004

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.240 AlteredExpression LHGDN Vitamin D receptor agonists induce prostatic acid phosphatase to reduce cell growth and HER-2 signaling in LNCaP-derived human prostate cancer cells. 16076555

2005

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.240 GeneticVariation BEFREE Here we describe in detail the construction of a recombinant variant of FPV expressing the prostate tumor-associated antigen prostatic acid phosphatase (PAP) in conjunction with the immunostimulatory cytokine, interleukin-2 (IL-2), which, if undertaken under the appropriate regulatory conditions and with approvals in place, would theoretically be amenable to clinical trial applications. 24619696

2014

Entrez Id: 84519
Gene Symbol: ACRBP
ACRBP
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model. 17013881

2007

Entrez Id: 2181
Gene Symbol: ACSL3
ACSL3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression LHGDN Vitamin D3 inhibits fatty acid synthase expression by stimulating the expression of long-chain fatty-acid-CoA ligase 3 in prostate cancer cells. 15556626

2004

Entrez Id: 2182
Gene Symbol: ACSL4
ACSL4
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model. 17013881

2007

Entrez Id: 6296
Gene Symbol: ACSM3
ACSM3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human Microarray comparison of prostate tumor gene expression in African-American and Caucasian American males: a pilot project study. 19208208

2009

Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 Biomarker BEFREE Recent findings established that this steroidal drug exhibits potent apoptotic responses in prostate tumors in vitro and in vivo, by affecting key signaling orchestrating proliferation and apoptosis, such as c-Myc and caspase 3, Rho GTPases and actin cytoskeleton dynamics. 28704809

2017

Entrez Id: 92
Gene Symbol: ACVR2A
ACVR2A
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression LHGDN Because prostate tumors appear to have a high incidence of MSI, we analyzed prostate cancer cell lines, with and without MSI, for ACVR2 and TGFbetaR2 mutations. 16337854

2005

Entrez Id: 102
Gene Symbol: ADAM10
ADAM10
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 GeneticVariation LHGDN Nuclear translocation of ADAM-10 contributes to the pathogenesis and progression of human prostate cancer. 17727679

2007

Entrez Id: 8751
Gene Symbol: ADAM15
ADAM15
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 Biomarker LHGDN Taken together, these data strongly support a functional role for ADAM15 in prostate tumor cell interaction with vascular endothelium and the metastatic progression of human prostate cancer. 18281484

2008

Entrez Id: 8751
Gene Symbol: ADAM15
ADAM15
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 Biomarker BEFREE Taken together, these data strongly support a functional role for ADAM15 in prostate tumor cell interaction with vascular endothelium and the metastatic progression of human prostate cancer. 18281484

2008

Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.020 AlteredExpression BEFREE Here, we provide evidence that PTEN loss in prostate tumours upregulates the expression of ADAM17, thereby activating NOTCH signalling. 27941799

2016

Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.020 Biomarker LHGDN Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas. 14532978

2003

Entrez Id: 10863
Gene Symbol: ADAM28
ADAM28
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 Biomarker CTD_human Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets. 29662167

2018

Entrez Id: 10863
Gene Symbol: ADAM28
ADAM28
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 AlteredExpression BEFREE The results of this study provide important insights into the role of metalloproteinases in human prostate cancer.The expression of ADAM28 protein levels was assessed within human prostate tumors and normal adjacent tissue by immunohistochemistry. 27749584

2016

Entrez Id: 8754
Gene Symbol: ADAM9
ADAM9
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 AlteredExpression LHGDN ADAM9 expression is a significant and independent prognostic marker of PSA relapse in prostate cancer. 18061337

2008

Entrez Id: 8754
Gene Symbol: ADAM9
ADAM9
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Biomarker CTD_human Oxidative stress induces ADAM9 protein expression in human prostate cancer cells. 17018608

2006

Entrez Id: 8754
Gene Symbol: ADAM9
ADAM9
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Biomarker LHGDN Reactive oxygen species mediate androgen receptor- and serum starvation-elicited downstream signaling of ADAM9 expression in human prostate cancer cells. 17342749

2007