Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 AlteredExpression BEFREE Employing quantitative real-time PCR, we determined that expression of mitochondrial acetyl-CoA carboxylase 2 (ACC2) was increased by 50% with obesity (P < 0.05). 16721829

2006
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 Biomarker CTD_human Orchestrated downregulation of genes involved in oxidative metabolic pathways in obese vs. lean high-fat young male consumers. 20882379

2011
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 Biomarker BEFREE Recombinant yeast screen for new inhibitors of human acetyl-CoA carboxylase 2 identifies potential drugs to treat obesity. 20439761

2010
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 AlteredExpression BEFREE In conclusion, common polymorphisms of ACACB gene are associated with obesity and, independently, with type 2 diabetes in postmenopausal women, suggesting that the activity of acetyl-CoA carboxylase beta plays an important role in these disorders related to energy metabolism. 21908218

2011
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 Biomarker BEFREE ACC2 as well as CPT1 are therefore potential targets to treat components of the metabolic syndrome such as obesity and insulin resistance. 19694967

2010