Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 Biomarker CTD_human Orchestrated downregulation of genes involved in oxidative metabolic pathways in obese vs. lean high-fat young male consumers. 20882379

2011
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 AlteredExpression BEFREE In conclusion, common polymorphisms of ACACB gene are associated with obesity and, independently, with type 2 diabetes in postmenopausal women, suggesting that the activity of acetyl-CoA carboxylase beta plays an important role in these disorders related to energy metabolism. 21908218

2011
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 Biomarker BEFREE Recombinant yeast screen for new inhibitors of human acetyl-CoA carboxylase 2 identifies potential drugs to treat obesity. 20439761

2010
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 Biomarker BEFREE ACC2 as well as CPT1 are therefore potential targets to treat components of the metabolic syndrome such as obesity and insulin resistance. 19694967

2010
Entrez Id: 32
Gene Symbol: ACACB
ACACB
CUI: C0028754
Disease: Obesity
Obesity 		0.340 AlteredExpression BEFREE Employing quantitative real-time PCR, we determined that expression of mitochondrial acetyl-CoA carboxylase 2 (ACC2) was increased by 50% with obesity (P < 0.05). 16721829

2006