×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Effects of bromocriptine on blood pressure and plasma beta-endorphin in spontaneously hypertensive rats.
6274577
1981
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Vasodilator prostanoids and ACTH -dependent hypertension .
6135010
1983
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Adrenocorticotrophic hormone-induced hypertension in the rat: effects of the endothelin antagonist bosentan.
10474778
1999
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
The anti-oxidant Tempol reverses and partially prevents adrenocorticotrophic hormone-induced hypertension in the rat.
12872045
2003
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Thus, NAC partially prevented but did not reverse ACTH -induced hypertension .
16546835
2006
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
ACTH hypertension in the rat: role of sodium chloride.
1321011
1992
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
11193135
2000
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Lipopolysaccharide reverses adrenocorticotrophic hormone-induced hypertension in the rat.
12887135
2003
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
These studies suggest that a steroid other than aldosterone, 18-OH-DOC, or DOC may be the cause of the ACTH -induced hypertension in this patient.
187612
1976
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Exaggerated natriuresis in ACTH hypertension in sheep.
216942
1978
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Influence of somatostatin analogue (SMS 201-995, octreotide) on blood pressure in adrenocorticotrophin (ACTH) treated rats: role of hyperinsulinaemia in ACTH hypertension.
8261660
1993
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Dexamethasone-responsive hypertension in young women with suppressed renin and aldosterone.
76749
1978
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Effect of sodium depletion on pressor responsiveness in ACTH -induced hypertension in man.
2822310
1987
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Potentiation of ACTH hypertension in man with salt loading.
2992854
1985
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Children who develop hypertension during ACTH therapy should be considered at risk for hypertrophic cardiomyopathy and should undergo routine echocardiographic evaluation.
2821097
1987
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Telemetric monitoring of adrenocorticotrophin-induced hypertension in mice.
11560123
2001
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Based on the various biological effects of ACTH different explanations are proposed: oedema or deposition of glycogen in the myocardial tissue, hyperinsulinism, arterial hypertension and increased inotropic stimulus.
6088243
1984
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Overall, the data establish that the alpha(2)-Na(+)-K(+)-ATPase ouabain-binding site is of central importance in the development of ACTH -induced hypertension .
18487447
2008
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Effects of bromocriptine on blood pressure and plasma beta-endorphin in spontaneously hypertensive rats.
6274577
1981
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Effect of sodium depletion on pressor responsiveness in ACTH -induced hypertension in man.
2822310
1987
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
These studies suggest that a steroid other than aldosterone, 18-OH-DOC, or DOC may be the cause of the ACTH -induced hypertension in this patient.
187612
1976
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Inhibition of NO synthesis has an additive effect on hypertension induced by ACTH in conscious rats.
1330390
1992
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
In man ACTH produces systolic hypertension which can be reproduced by infusion of cortisol, but not deoxycorticosterone, at rates appropriate for conditions of ACTH stimulation.
3001556
1985
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Cushing's disease in dogs and humans.
19153526
2009
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Cushing's syndrome secondary to ACTH-secreting Wilms' tumor.
4367732
1974