×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer.
19836313
2009
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary.
26446593
2016
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Adaptive variation in environmental and genetic sex determination in a fish.
3561487
1987
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Expanded extracolonic tumor spectrum in MUTYH-associated polyposis.
19732775
2009
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
BRAF mutations in multiple sebaceous hyperplasias of patients belonging to MYH-associated polyposis pedigrees.
17273161
2007
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis.
18091433
2007
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
LOVD v.2.0: the next generation in gene variant databases.
21520333
2011
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH.
27194394
2016
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
The thorough screening of the MUTYH gene in a large French cohort of sporadic colorectal cancers.
17931073
2007
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype.
16557584
2006
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.
26824983
2016
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Similar colorectal cancer risk in patients with monoallelic and biallelic mutations in the MYH gene identified in a population with adenomatous polyposis.
17949294
2007
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli.
16134147
2005
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
27978560
2017
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Analysis of inherited MYH/(MutYH) mutations in British Asian patients with colorectal cancer.
17369389
2007
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Genetic instability in lymphoblastoid cell lines expressing biallelic and monoallelic variants in the human MUTYH gene.
24569162
2014
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
20848659
2010
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
MUTYH-associated polyposis - variability of the clinical phenotype in patients with biallelic and monoallelic MUTYH mutations and report on novel mutations.
20618354
2010
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
GeneticVariation
CLINVAR
Immunohistochemical expression of MYH protein can be used to identify patients with MYH-associated polyposis.
16890597
2006
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Patterns and functional implications of rare germline variants across 12 cancer types.
26689913
2015
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.
21171015
2011
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
The first mutations in the MYH gene reported in Moroccan colon cancer patients.
22266422
2012
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Identification of a patient with atypical MUTYH-associated polyposis through detection of the KRAS c.34G>T mutation in liver metastasis.
23341527
2013
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
Biomarker
CLINGEN
Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6.
11801590
2002
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Colorectal Adenomatous Polyposis, Autosomal Recessive
0.710
CausalMutation
CLINVAR
Characterization of mutant MUTYH proteins associated with familial colorectal cancer.
18534194
2008