Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.420 Biomarker CTD_human Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31. 24728293

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.420 Biomarker PSYGENET In the present study we chose to investigate 7 genes involved in the synthesis, degradation and transportation of RA, ALDH1A1, ALDH1A2, ALDH1A3, CYP26A1, CYP26B1, CYP26C1 and Transthyretin (TTR), for their roles in the development of schizophrenia. 19703508

2009
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.320 Biomarker CTD_human Taken together, our findings implicate ALDH1a2 as a candidate tumor suppressor gene in prostate cancer and further support a role of retinoids in the prevention or treatment of prostate cancer. 16166285

2005
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0025312
Disease: Meningomyelocele
Meningomyelocele 		0.310 Biomarker CTD_human These results may suggest that polymorphisms in ALDH1A2 may influence the risk for lumbosacral myelomeningocele in humans. 16237707

2005
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.310 Biomarker CTD_human Using bisulfite sequencing, we determined that the ALDH1a2 promoter region was significantly hypermethylated in primary prostate tumors compared with normal prostate specimens (P = 0.01). 16166285

2005
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0086743
Disease: Osteoarthrosis Deformans
Osteoarthrosis Deformans 		0.300 Biomarker CTD_human Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31. 24728293

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0242422
Disease: Parkinsonian Disorders
Parkinsonian Disorders 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0242423
Disease: Ramsay Hunt Paralysis Syndrome
Ramsay Hunt Paralysis Syndrome 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0752097
Disease: Autosomal Dominant Juvenile Parkinson Disease
Autosomal Dominant Juvenile Parkinson Disease 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0752098
Disease: Autosomal Dominant Parkinsonism
Autosomal Dominant Parkinsonism 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0752100
Disease: Autosomal Recessive Parkinsonism
Autosomal Recessive Parkinsonism 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0752101
Disease: Parkinsonism, Experimental
Parkinsonism, Experimental 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0752104
Disease: Familial Juvenile Parkinsonism
Familial Juvenile Parkinsonism 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0752105
Disease: Parkinsonism, Juvenile
Parkinsonism, Juvenile 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C1868675
Disease: PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE
PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE 		0.300 Biomarker CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800

2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0086664
Disease: Myelocele
Myelocele 		0.300 Biomarker CTD_human Analysis of ALDH1A2, CYP26A1, CYP26B1, CRABP1, and CRABP2 in human neural tube defects suggests a possible association with alleles in ALDH1A2. 16237707

2005
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
CUI: C0751316
Disease: Acquired Meningomyelocele
Acquired Meningomyelocele 		0.300 Biomarker CTD_human Analysis of ALDH1A2, CYP26A1, CYP26B1, CRABP1, and CRABP2 in human neural tube defects suggests a possible association with alleles in ALDH1A2. 16237707

2005