Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.240 Biomarker BEFREE These findings indicate that leptin and TNFα are associated with IPFD independent of abdominal fat distribution and other covariates in individuals after AP. 31054479

2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.240 Biomarker BEFREE This study aimed to evaluate the effects of leptin on the intestinal mucosal barrier and inflammatory injury in obese mice with AP. 29934609

2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.240 AlteredExpression BEFREE Taken together, exogenous leptin administration regulated inflammatory factors and the expression of OB‑Rb at the early stage of AP, which exerted protective effects by through the immunological and endocrinal pathways. 28849043

2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.240 Biomarker RGD Hepatic steatosis depresses alpha-1-antitrypsin levels in human and rat acute pancreatitis. 26634430

2015
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.240 Biomarker BEFREE The aim of the present study was: (1) to assess plasma leptin levels in rats with caerulein-induced pancreatitis (CIP) and humans with acute pancreatitis; and (2) to determine the effects of exogenous leptin on the course of acute CIP in rats. 12138320

2002