Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 145624
Gene Symbol: PWAR1
PWAR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 Biomarker BEFREE Finally, we review the connections between disruptions in PAR-1/MARK function and Alzheimer's disease and cancer. 28236972

2017
Entrez Id: 145624
Gene Symbol: PWAR1
PWAR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 PosttranslationalModification BEFREE Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer's disease treatment. 27708431

2016
Entrez Id: 145624
Gene Symbol: PWAR1
PWAR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 PosttranslationalModification BEFREE Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1. 22952452

2012
Entrez Id: 145624
Gene Symbol: PWAR1
PWAR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 Biomarker BEFREE The kinase MARK2/Par-1 plays key roles in several cell processes, including neurodegeneration such as Alzheimer disease by phosphorylating tau and detaching it from microtubules. 22238344

2012
Entrez Id: 145624
Gene Symbol: PWAR1
PWAR1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 Biomarker BEFREE Microtubule affinity regulating kinase (MARK) and PAR-1 have been identified as physiological tau kinases, and aberrant phosphorylation of MARK/PAR-1 target sites in tau has been observed in AD patients and animal models. 17234589

2007