×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
GWASCAT
Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.
30929738 2019
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
GWASCAT
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
29785011 2018
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
GWASCAT
Identification of Four Novel Loci in Asthma in European American and African American Populations.
27611488 2017
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
BEFREE
Our findings first suggested that the variants in RAD50 -IL13 region were not associated with asthma risk in Northeastern Han Chinese children.
26365633 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
Biomarker
BEFREE
IL13, rather than RAD50 , IL4, or IL5, is more likely to be the asthma susceptibility gene.
27050946 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
GWASCAT
Detection and interpretation of shared genetic influences on 42 human traits.
27182965 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
BEFREE
This is the first study validating that IL33, IL1R1, and RAD50 genes are associated with the risk of asthma in Chinese population.
26493291 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
BEFREE
Genomewide association and epigenetic studies found a region within the RAD50 gene on chromosome 5q31 to be associated with total serum IgE levels and asthma .
24866380 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
Biomarker
CTD_human
Four of these, GSDMB, IL33, RAD50 and IL1RL1, were previously reported as asthma susceptibility loci, but the effect sizes for these loci in our cohort were considerably larger than in the previous genome-wide association studies of asthma .
24241537 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
Biomarker
BEFREE
Interestingly, these differences clustered in the genes highly associated with asthma (ORMDL family) and IgE regulation (RAD50 , IL13, and IL4), but not in the T-regulatory genes (FOXP3, RUNX3).
23346934 2013
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
GWASDB
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.
21907864 2011
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
BEFREE
When adjusted for race and gender, only rs2706347 in RAD50 remained significantly associated with asthma .
21734400 2011
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
GWASCAT
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.
20159242 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
GWASDB
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.
20159242 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
GWASDB
A large-scale, consortium-based genomewide association study of asthma.
20860503 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
BEFREE
Multiple SNPs in the RAD50 -IL13 region on chromosome 5q31.1 were associated with asthma : rs2244012 in intron 2 of RAD50 (P = 3.04E-07).
20159242 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Asthma
0.480
GeneticVariation
BEFREE
Polymorphisms within the RAD50 gene on chromosome 5q31 were consistently associated with IgE levels (P values 6.28 x 10(-7)-4.46 x 10(-8)) and increased the risk for atopic eczema and asthma .
18846228 2008