Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.340 Biomarker BEFREE High-Fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via Interleukin 8 and Alterations to the Gut Microbiome. 30998992

2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.340 AlteredExpression BEFREE The increased basal expression levels of IL-8 with the progression of Barrett's esophagus constrain NFκB activation and its contribution in the manifestation of Barrett's esophagus. 29086334

2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.340 Biomarker BEFREE The induction of IL8 was more evident in BE compared to normal squamous esophagus. 23955118

2014
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.340 AlteredExpression BEFREE In patients with reflux, Nissen fundoplication led to significantly decreased IL-8 expression compared with preoperative levels in esophagitis (P = .01) and Barrett's esophagus (P = .03). 17576892

2007
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.340 Biomarker CTD_human Activation of NFkappaB represents the central event in the neoplastic progression associated with Barrett's esophagus: a possible link to the inflammation and overexpression of COX-2, PPARgamma and growth factors. 15387324

2004