Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006012
Disease: Borderline Personality Disorder
Borderline Personality Disorder
0.060 GeneticVariation BEFREE Methylation alterations in ASPD and BPD repeatedly affected <i>HTR2A, HTR3A, NR3C1</i>, and <i>MAOA</i> genes. 30510522

2018

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006012
Disease: Borderline Personality Disorder
Borderline Personality Disorder
0.060 GeneticVariation BEFREE The association of 5-HTR2A-1438A/G, COMTVal158Met, MAOA-LPR, DATVNTR and 5-HTTVNTR gene polymorphisms and borderline personality disorder in female heroin-dependent Chinese subjects. 24355137

2014

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006012
Disease: Borderline Personality Disorder
Borderline Personality Disorder
0.060 PosttranslationalModification BEFREE For HTR2A the average methylation of four CpG sites was 0.8% higher in BPD patients compared to controls (p = 0.002). 22139575

2011

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006012
Disease: Borderline Personality Disorder
Borderline Personality Disorder
0.060 Biomarker BEFREE However, there were significant associations between HTR2A and personality traits in the BPD patients. 17000047

2006

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006012
Disease: Borderline Personality Disorder
Borderline Personality Disorder
0.060 AlteredExpression BEFREE Subjects with MDD have a significant decrease in 5-HT(1A) mRNA in the HC; subjects with BPD and schizophrenia had increased 5-HT(1B) mRNA levels and a significant decrease in 5-HT(2A) mRNA levels in the hippocampal formation. 14744462

2004

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006012
Disease: Borderline Personality Disorder
Borderline Personality Disorder
0.060 GeneticVariation BEFREE Inpatient alcohol dependents showed a significant association between 5-HT2A A alleles and impulsive traits, independent of the presence of APD or BPD. 11287798

2001