Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.070 Biomarker BEFREE Together, the identification of the ERβ-HOTAIR axis may provide us new biomarkers and/or therapeutic targets to better suppress RCC progression in the future. 29789714

2018

Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.070 Biomarker BEFREE However, HOTAIR suppression resulted in the similar functional effects in the same RCC cell lines. 29440295

2018

Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.070 AlteredExpression BEFREE Overexpression of HOTAIR promoted the capability of proliferation, migration and invasion in RCC cell lines. 30105850

2018

Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.070 Biomarker BEFREE Collectively, these data suggest that HOTAIR is an important promoter in metastasis of renal cell carcinoma and also plays a dual regulatory role in chromatin state by effecting both histone metylation and demethylation at different gene loci. 28177890

2017

Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.070 Biomarker BEFREE In conclusion, these results suggest that HOTAIR promotes Rcc tumorigenesis via miR-217/HIF-1α/AXL signaling, which may provide a new target for the diagnosis and therapy of Rcc disease. 28492542

2017

Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.070 Biomarker BEFREE HOTAIR could be a potential therapeutic target in RCC. 28938586

2017

Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.070 Biomarker BEFREE HOTAIR expression is correlated with the migration of RCC cells, and HOTAIR may be involved in the curcumin-induced inhibition of RCC metastasis. 24935377

2014