Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 AlteredExpression BEFREE Here, we found that circular RNA (circCTIC1) was highly expressed in colon tumor and colon TICs. circCTIC1 knockdown impaired the self-renewal of colon TICs, and its overexpression played an opposite role. circCTIC1 promoted the expression of c-Myc and drove the self-renewal of colon TIC through c-Myc-dependent manner. circCTIC1 interacted with nuclear remodeling factor (NURF) complex, recruited NURF complex onto c-Myc promoter and finally drove the transcriptional initiation of c-Myc. 30403769

2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 Therapeutic RGD MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach. 22641368

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 Biomarker CTD_human Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate. 21081470

2011
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 Biomarker CTD_human Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat. 18283038

2008
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 AlteredExpression LHGDN Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ROCK and c-Myc. 16543245

2006
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 AlteredExpression BEFREE Activation of c-MYC and c-MYB proto-oncogenes is associated with decreased apoptosis in tumor colon progression. 11848471

2002
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 Biomarker CTD_human Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents. 12189186

2002