Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 90226
Gene Symbol: UCN2
UCN2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.360 Biomarker BEFREE We previously reported that urocortin 2 (Ucn2) gene transfer increases heart function in mice with heart failure with reduced ejection fraction. 31676153

2020
Entrez Id: 90226
Gene Symbol: UCN2
UCN2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.360 Biomarker BEFREE Peptide infusions of peptides the corticotropin releasing factor family, including urocortin 2, stresscopin, and urocortin 3 (UCn3), have favorable acute effects in clinical heart failure (HF), but their short half-lives make them unsuitable for chronic therapy. 30003813

2019
Entrez Id: 90226
Gene Symbol: UCN2
UCN2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.360 Biomarker BEFREE Urocortin-2 (Ucn-2) has shown promising therapeutic effects in experimental and clinical left ventricular heart failure (HF). 29584808

2018
Entrez Id: 90226
Gene Symbol: UCN2
UCN2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.360 Biomarker BEFREE All three Ucns exert salutary hemodynamic, neurohormonal and renal effects in experimental heart failure and recent clinical trials have demonstrated hemodynamic benefits of Ucn2 administration. 28887029

2017
Entrez Id: 90226
Gene Symbol: UCN2
UCN2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.360 AlteredExpression BEFREE Moreover, plasma Ucn2 levels were 7.5-fold higher in patients with heart failure compared to those in healthy controls. 28550160

2017
Entrez Id: 90226
Gene Symbol: UCN2
UCN2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.360 Biomarker BEFREE Urocortin-2 (UCn2) peptide infusion increases cardiac function in patients with heart failure, but chronic peptide infusion is cumbersome, is costly, and provides only short-term benefits. 25760560

2015
Entrez Id: 90226
Gene Symbol: UCN2
UCN2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.360 Therapeutic CTD_human Ucn2 has marked and beneficial hemodynamic, hormonal, and renal effects in experimental HF. 16330704

2005