Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.340 Biomarker BEFREE PLWH had a higher median AAT concentration than uninfected controls [1.4 (interquartile range (IQR) 1.3-1.6) versus 1.3 (IQR 1.2-1.4) g/L; P < 0.0001] and HIV infection was independently associated with higher AAT concentration [adjusted β = 0.10 g/L; 95% confidence interval (CI) 0.08; 0.11 g/L; P < 0.001]. 30160349

2018
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.340 Biomarker BEFREE These results suggest that deficiency in A1AT may be a risk factor for acquisition of HIV infection, but physiological A1AT concentrations do not affect disease progression after infection occurs. 24122823

2014
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.340 Therapeutic CTD_human Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide. 17448989

2007
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.340 AlteredExpression BEFREE SV[LTR](AT) was designed so that synthesis of human alpha(1)AT would be trans-activated by HIV infection. 14625571

2003
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.340 GeneticVariation BEFREE Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease? 14551891

2003