Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.310 AlteredExpression BEFREE LPS-induced hyperalgesia was associated with a decrease in eNOS, nNOS, and iNOS protein expression and activity as well as an increase in expression of NF-κB p65, caspase-1 p20, caspase-11 p20, NLRP3, ASC, gp91<sup>phox</sup>, p47<sup>phox</sup>, and nitrotyrosine proteins in addition to elevated IL-1β levels. 27924425

2017
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.310 Biomarker CTD_human In streptozotocin-induced hyperalgesia, inducible NO synthase participates in pronociceptive activity of bradykinin, whereas in vincristine-induced hyperalgesia bradykinin seemed to activate neuronal NO synthase pathway. 19300402

2009
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.310 Biomarker CTD_human Effect of cyclooxygenase and nitric oxide synthase inhibitors on streptozotocin-induced hyperalgesia in rats. 17989504

2008