Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.550 AlteredExpression BEFREE Here, we investigated the influence of regulator of G protein signaling 5 (RGS5), an inhibitor of Gα<sub>q/11</sub> and Gα<sub>i/o</sub> activity, on blood pressure and the VSMC phenotype during experimental hypertension. 29208700

2018
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.550 Biomarker BEFREE This is consistent with dysregulated (RGS5-mediated) AT<sub>1</sub>R signaling that could contribute to excessive vasoconstriction in hypertension. 29061726

2017
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.550 GeneticVariation BEFREE In this study, we investigated the association between RGS5 gene variants and hypertension in the Mongolian and Han populations. 26782409

2015
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.550 Therapeutic RGD Antihypertensive effects of peroxisome proliferator-activated receptor-β activation in spontaneously hypertensive rats. 21825230

2011
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.550 GeneticVariation BEFREE The strongest signal for hypertension was for rs2815272 in the RGS5 gene (P = 9.3 × 10). 21881522

2011
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.550 Biomarker BEFREE Multiple SNPs in combination in RGS5 may confer risk for hypertension. 19863299

2009
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.550 Therapeutic CTD_human [A muscle mutant of Drosophila melanogaster: the electron microscopic study of the indirect flight musculature]. 1798635

1992