Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.150 GeneticVariation BEFREE We aimed to characterize the pathogenicity of a novel GLA gene mutation identified during hemodialysis screening and the histologic findings of early Fabry nephropathy. 28892806

2018
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.150 GeneticVariation BEFREE Identification of a novel GLA mutation (Y88C) in a Korean family with Fabry nephropathy: a case report. 27776503

2016
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.150 AlteredExpression BEFREE Downregulation of alpha-galactosidase A upregulates CD77: functional impact for Fabry nephropathy. 19037253

2009
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.150 GeneticVariation BEFREE Point mutation in the alpha-galactosidase A gene of atypical Fabry disease with only nephropathy. 8738659

1996
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.150 Biomarker BEFREE As the genetic and pathophysiologic basis of renal disease is clarified, obvious targets for therapy will be defined, for example, polycystin in polycystic kidney disease, human immunodeficiency virus (HIV) type 1 in HIV-associated nephropathy, alpha-galactosidase A in Fabry's disease, insulin in diabetic nephropathy, and the "minor" collagen IV chains in Alport's syndrome. 8840936

1996
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.150 Biomarker HPO