Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.360 Biomarker BEFREE TLR2-deficient mice exacerbated renal injury in cisplatin-induced AKI, with higher serum creatinine and blood urea nitrogen, more severe morphological injury compared with that of wild-type mice. 30387162

2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.360 Biomarker BEFREE For the present study, it was hypothesized that TLR2 inhibition could reduce inflammation and consequently prevent septic AKI. 31798708

2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.360 Biomarker BEFREE Adoptive transfer of TLR-2-primed WTDCs significantly expanded Tregs in the kidneys of CDDP-treated WT and Gal-3<sup>-/-</sup> recipients resulting in the suppression of IFN-γ and IL-17-driven inflammation and alleviation of AKI. 31534532

2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.360 Biomarker CTD_human Relevance of megalin receptor injury with nuclear factor-kappa B upregulation in acute kidney injury induced in rats. 29286200

2018
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.360 Biomarker BEFREE Hence, the present study aimed to evaluate the specific participation of TLR2 and TLR4 molecules on the development of cisplatin-induced AKI. 29500224

2018
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.360 Biomarker BEFREE We propose that the TLR1/TLR2 heterodimer may be a new therapeutic target for the prevention of acute kidney injury in diabetic patients. 28822965

2017
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.360 Biomarker BEFREE Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury. 24480070

2014