Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.340 GeneticVariation BEFREE Janus kinase 3 (JAK3) tyrosine kinase has a central role in the control of lymphopoiesis, and mutations in JAK3 can lead to either severe combined immunodeficiency or leukemia and lymphomas. 30560087

2018
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.340 GeneticVariation BEFREE JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma. 23689514

2014
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.340 GeneticVariation BEFREE Twelve SNPs were significantly associated with the risk of lymphoma (P(trend)<0.05) in six genes (IL1RN, IL2, IL12RB1, JAK3, TNFRSF13B, and XRCC3). 22524835

2012
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.340 Biomarker BEFREE Moreover, primary lymphoma samples revealed that a number of these genes were reciprocally regulated during disease progression and JAK3 inhibition suggesting that downstream targets of JAK3 could be exploited in the development of novel cancer treatment regimes. 20211620

2010
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.340 CausalMutation CGI