×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
Biomarker
BEFREE
Therefore, this study is to clarify the mechanism by which LINC00319 sponges <i>miR-335 -5p</i> to influence development of GC .
31433213
2020
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
Biomarker
BEFREE
Rho-associated coiled-coil forming protein kinase l (ROCK1) is characterized as pivotal downstream effectors of the small GTPase RhoA and reported to participate in tumor metastasis. miR-335 -5p acts as tumor suppressor microRNA and is identified to be downregulated in tumor tissues. miR-335-5p/ROCK1 axis has been demonstrated to promote cell proliferation and metastasis in gastric cancer , hepatocellular carcinoma and so on.
31140617
2019
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
AlteredExpression
BEFREE
Quantitative real-time PCR showed that miR-335 -5p expression was downregulated and negatively correlated with ZEB1-AS1 expression in GC tissues.
29215918
2018
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
Biomarker
BEFREE
NEAT1-miR-335 -5p-ROCK1 axis may be a potential therapeutic strategy for gastric cancer therapy.
29544562
2018
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
Biomarker
BEFREE
As identified by bioinformatics analysis, miR-335 was shown to be the top-ranked miRNA implicated in GC .
30171475
2018
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
AlteredExpression
BEFREE
Low levels of miR-335 expression and high levels of miR-335 methylation in GC tissues were associated with poor clinical features and prognosis.
28239297
2017
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
PosttranslationalModification
BEFREE
DNA methylation of miR-335 may be a promissory strategy for non-invasive approach to gastric cancer .
29075357
2017
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
AlteredExpression
BEFREE
Long non-coding RNA MSTO2P promotes the proliferation and colony formation in gastric cancer by indirectly regulating miR-335 expression.
28618927
2017
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
Biomarker
BEFREE
The regulative role of miR-335 and miR-34a over GC cell growth, apoptosis, and invasion was studied using Cell Counting Kit-8 (CCK-8) assay, flow cytometry, and transwell assay, respectively.
26318298
2016
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
Biomarker
BEFREE
MiR-335 has recently been identified to be involved in tumorigenesis of several cancers such as ovarian cancer and gastric cancer .
25337272
2014
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
AlteredExpression
BEFREE
The expression of miR-335 in gastric cancer and its effects are not known.
21822301
2012
×
Entrez Id:
442904
Gene Symbol:
MIR335
MIR335
Malignant neoplasm of stomach
0.100
AlteredExpression
BEFREE
A high frequency recurrence and poor survival were observed in GC cases with high level of hsa-miR-335 (P<0.001).
22802949
2012