Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 Biomarker BEFREE Therefore, this study is to clarify the mechanism by which LINC00319 sponges <i>miR-335-5p</i> to influence development of GC. 31433213

2020

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 Biomarker BEFREE Rho-associated coiled-coil forming protein kinase l (ROCK1) is characterized as pivotal downstream effectors of the small GTPase RhoA and reported to participate in tumor metastasis. miR-335-5p acts as tumor suppressor microRNA and is identified to be downregulated in tumor tissues. miR-335-5p/ROCK1 axis has been demonstrated to promote cell proliferation and metastasis in gastric cancer, hepatocellular carcinoma and so on. 31140617

2019

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 AlteredExpression BEFREE Quantitative real-time PCR showed that miR-335-5p expression was downregulated and negatively correlated with ZEB1-AS1 expression in GC tissues. 29215918

2018

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 Biomarker BEFREE NEAT1-miR-335-5p-ROCK1 axis may be a potential therapeutic strategy for gastric cancer therapy. 29544562

2018

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 Biomarker BEFREE As identified by bioinformatics analysis, miR-335 was shown to be the top-ranked miRNA implicated in GC. 30171475

2018

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 AlteredExpression BEFREE Low levels of miR-335 expression and high levels of miR-335 methylation in GC tissues were associated with poor clinical features and prognosis. 28239297

2017

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 PosttranslationalModification BEFREE DNA methylation of miR-335 may be a promissory strategy for non-invasive approach to gastric cancer. 29075357

2017

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 AlteredExpression BEFREE Long non-coding RNA MSTO2P promotes the proliferation and colony formation in gastric cancer by indirectly regulating miR-335 expression. 28618927

2017

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 Biomarker BEFREE The regulative role of miR-335 and miR-34a over GC cell growth, apoptosis, and invasion was studied using Cell Counting Kit-8 (CCK-8) assay, flow cytometry, and transwell assay, respectively. 26318298

2016

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 Biomarker BEFREE MiR-335 has recently been identified to be involved in tumorigenesis of several cancers such as ovarian cancer and gastric cancer. 25337272

2014

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 AlteredExpression BEFREE The expression of miR-335 in gastric cancer and its effects are not known. 21822301

2012

Entrez Id: 442904
Gene Symbol: MIR335
MIR335
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.100 AlteredExpression BEFREE A high frequency recurrence and poor survival were observed in GC cases with high level of hsa-miR-335 (P<0.001). 22802949

2012