Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 Biomarker BEFREE Hypermethylated long noncoding RNA MEG3 promotes the progression of gastric cancer. 31584879

2019
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 AlteredExpression BEFREE The results of current study demonstrated that combination of H19, MEG3 and miR-675-5p expression levels could provide a potential diagnostic panel for GC. 30447342

2019
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 Biomarker BEFREE Thus, these data indicated that miR-208a promoted GC progression by targeting SFRP1 and negatively regulating MEG3, which may be a potential therapeutic target of GC. 29886152

2018
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 AlteredExpression BEFREE Our data showed that down-regulated MEG3 was observed in GC tissues and cell lines (MKN74, MKN45, SGC7901, AGS). 29710493

2018
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 Biomarker BEFREE In the present study, we investigated the relationship between MEG3 and miR‑21 in regards to the cell mobility of gastric cancer. 29749532

2018
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 Biomarker BEFREE lncRNA MEG3 could inhibit the proliferation and metastasis of gastric cancer. 28975980

2017
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 Biomarker BEFREE Furthermore, conditional logistic regression analysis revealed the aberrant expression of CTD-2541M15, UCA1 and MEG3 closely linked with GC. 26718650

2016
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 AlteredExpression BEFREE MEG3 is decreased in GC patients and cell lines, and its expression was associated with metastatic GC. 26253106

2015
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 Biomarker BEFREE Several lncRNAs such as H19, HOTAIR and MEG3 have been found to be associated with miRNAs in gastric cancer (GC), generating regulatory crosstalk across the transcriptome. 26556995

2015
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 AlteredExpression BEFREE We found that expression of both miR-141 and MEG3 was significantly reduced in GC compared with levels in matched nonmalignant tissues. 26233544

2015
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 AlteredExpression BEFREE Our results suggest that the suppression of miR-148a may contribute to the down-regulation of MEG3 in gastric cancer by modulation of DNMT-1. 24515776

2014
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.100 AlteredExpression BEFREE In this study, to investigate the lncRNA MEG3 expression in gastric cancer, quantitative reverse-transcription polymerase chain reaction was conducted. 24006224

2014