Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 Biomarker BEFREE P-glycoprotein is a protective efflux transporter at the blood-brain barrier showing altered function in many neurological disorders. 27354093

2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 Biomarker CTD_human Methotrexate-induced subacute neurotoxicity in a child with acute lymphoblastic leukemia carrying genetic polymorphisms related to folate homeostasis. 21064136

2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 Biomarker CTD_human MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine. 17015054

2006
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 AlteredExpression BEFREE Because drug transporters such as P-glycoprotein, the product of the multidrug resistance (MDR1 ) gene, contribute to the function of the blood-brain barrier, we hypothesized that differences in their expression could affect the uptake of neurotoxic xenobiotics, thereby modulating interindividual susceptibility for neurological disorders such as Parkinson's disease. 12360103

2002