Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.060 GeneticVariation BEFREE Dual-luciferase reporter assays were conducted in neuroblastoma cells to assess the promoter transcriptional activity of the rs1024611 variants (T>C) and the GRCh38.p12chr17:34252593 G>C alleles in CCL2. 30761072

2019

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.060 AlteredExpression BEFREE In the present study, we investigated the mechanism of S1P-induced CCL2 expression in NB. 25092091

2014

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.060 AlteredExpression BEFREE Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival. 24626857

2014

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.060 Biomarker BEFREE We expressed firefly luciferase in CCR2b-expressing ATCs and observed improved homing (>10-fold) to CCL2-secreting neuroblastoma compared with CCR2-negative ATCs. 20842059

2010

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.060 Biomarker BEFREE MYCN knockdown in MYCN-amplified neuroblastoma cell lines restored CCL2 production and NKT cell chemoattraction. 17710228

2007

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.060 Biomarker BEFREE Supernatants of neuroblastoma cell lines that produced CCL2 induced in vitro migration of iNKTs from blood of patients and normal adults; this was abrogated by an anti-CCL2 monoclonal antibody. 15123743

2004