Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0027831
Disease: Neurofibromatosis 1
Neurofibromatosis 1 		0.050 GeneticVariation BEFREE All <i>NF1</i> variants were classified as pathogenic, according to the American College of Medical Genetics and Genomics and the Association for Molecular Pathology (ACMG-AMP) guidelines. 31443423

2019
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0027831
Disease: Neurofibromatosis 1
Neurofibromatosis 1 		0.050 Biomarker BEFREE Moreover, while all NF1-patient NPCs exhibit increased RAS activation and reduced cyclic AMP generation, there was a neurofibromin dose-dependent reduction in dopamine (DA) levels. 25788518

2015
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0027831
Disease: Neurofibromatosis 1
Neurofibromatosis 1 		0.050 Biomarker BEFREE The cyclic AMP pathway is a sex-specific modifier of glioma risk in type I neurofibromatosis patients. 25381154

2015
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0027831
Disease: Neurofibromatosis 1
Neurofibromatosis 1 		0.050 Biomarker BEFREE Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1. 20551058

2010
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0027831
Disease: Neurofibromatosis 1
Neurofibromatosis 1 		0.050 AlteredExpression BEFREE Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1. 17875698

2007