Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker CTD_human Augmented pulmonary responses to acute ozone exposure in obese mice: roles of TNFR2 and IL-13. 23434795

2013

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker GENOMICS_ENGLAND The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. 15358678

2004

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker CTD_human The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. 15358678

2004

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker BEFREE The involvement of CPE and THBS1 in obesity allows us to suggest that the physiological processes controlled by these genes contribute to depot and gender-related differences in the metabolic complications of obesity. 12530526

2002

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker MGD Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice. 12270926

2002

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker MGD Carboxypeptidase E (CPE) deficiency in mice with the fat mutation have reduced stomach function. 9893169

1999

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 GeneticVariation BEFREE Thus, genetic variation in the CPE gene does not appear to play a major role in the pathogenesis of NIDDM or obesity in Japanese subjects. 9662053

1998

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 GeneticVariation BEFREE A mutation of carboxypeptidase E (CPE), an enzyme active in the processing and sorting of prohormones, causes obesity in the fat/fat mouse. 9207799

1997

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker MGD Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice. 9019408

1997

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker MGD Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in cpefat mice associated with a carboxypeptidase E mutation. 9144234

1997

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker MGD Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity. 7663508

1995

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker MGD Atherosclerosis in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. 8177043

1994

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker MGD Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. 8177042

1994

Entrez Id: 1363
Gene Symbol: CPE
CPE
CUI: C0028754
Disease: Obesity
Obesity
0.730 Biomarker MGD Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse. 2250094

1991