Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia 		0.330 Biomarker CTD_human Supporting previous reports, the expression of sFlt-1 and PAI-1 were also upregulated in PE placentas. 18679377

2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia 		0.330 GeneticVariation LHGDN According to this analysis, the author proposes that the pattern of PAI-1 4G/5G polymorphism might represent a useful marker of increased risk for pre-eclampsia. 16502012

2006
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia 		0.330 GeneticVariation LHGDN However, women who are carriers of the G20210A prothrombin gene mutation and the PAI-1 5G/5G genotype are at risk for early onset of severe preeclampsia. 15842353

2005
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia 		0.330 GeneticVariation LHGDN Therefore, we assessed whether polymorphisms related to the transcriptional control of the PAI-1 gene (-675 4G/5G and -844G/A) are associated with mild preeclampsia. 12867763

2003