Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Biomarker BEFREE This study investigates the potential link between AngII-induced autophagy in the regulation of NLRP3 inflammasome/IL-1β axis in lung fibrosis. 29486589

2019
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Therapeutic CTD_human Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway. 31181250

2019
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Therapeutic CTD_human Angiotensin-(1-7)-mediated Mas1 receptor/NF-κB-p65 signaling is involved in a cigarette smoke-induced chronic obstructive pulmonary disease mouse model. 28960804

2018
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Biomarker BEFREE In vivo, AngII exacerbated bleomycin (BLM)-induced lung fibrosis in rats, and elevated mir-21 and the NLRP3 inflammasome. 29084974

2017
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Therapeutic RGD Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway. 24168260

2014
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 GeneticVariation BEFREE It is also the first to relate the effect of gender in lung fibrosis with polymorphisms in AGT. 23715995

2013
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Biomarker BEFREE Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage. 21487074

2011
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 AlteredExpression BEFREE The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis. 17630322

2007